Synthesis, ADMET and pharmacokinetic analysis of new isoxazolidine-pyrazole hybrids

Siwar Ghannay

View/Download PDF

Buy Reprints

PDF

Translate this page into:

Research Article

3 (

); 107-115

Synthesis, ADMET and pharmacokinetic analysis of new isoxazolidine-pyrazole hybrids

Siwar Ghannay

Received: 2024-03-17, Accepted: 2024-04-12, Published: 2024-10-27

Licence

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, transform, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

Disclaimer:
This article was originally published by Qassim University and was migrated to Scientific Scholar after the change of Publisher.

Abstract

Interest in hybrid compounds containing two or more different rings continues to grow due to the impressive biological results that have been derived in numerous examples. In this work, we have synthesized new isoxazolidine-pyrazole hybrids and study ADMET and pharmacokinetic analysis. These results outlined that the titled compounds have good ADMET properties, which are a requisite for a molecule to show acceptable drug-like and pharmacokinetic properties.