Pyrimidine-1,2,3-Triazole Hybrid Glycosides: Click Based Synthesis and Biological aspects

Mohamed EL-Bayaa

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Research Article

3 (

); 177-203

Pyrimidine-1,2,3-Triazole Hybrid Glycosides: Click Based Synthesis and Biological aspects

Mohamed EL-Bayaa

Received: 2024-06-09, Accepted: 2024-09-16, Published: 2024-10-27

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This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, transform, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

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This article was originally published by Qassim University and was migrated to Scientific Scholar after the change of Publisher.

Abstract

Application of click chemistry for the construction of hybrid structure incorporating 1,2,3-triazole nucleus was extensively studied as a powerful strategy for designing a variety of targeted structures. The currents review focused on the synthetic pathways of compounds possessing two important motifs: pyrimidine and 1,2,3-triazole systems and their derived sugar derivatives as glycoside analogues. The reported bioactivities of the formed hybrid products were highlighted.