1,3,4-Thiadiazole: Their sugar and isoindole derivatives and Biological activities.

Ahad El-Enazy; Wael A. El-Sayed; Fahad M. Alminderej; Abuzar E. A. E. Albadri

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Research Article

2 (

); 119-146

1,3,4-Thiadiazole: Their sugar and isoindole derivatives and Biological activities.

Ahad El-Enazy, Wael A. El-Sayed, Fahad M. Alminderej, Abuzar E. A. E. Albadri

Received: 2023-06-01, Accepted: 2023-06-18, Published: 2024-01-28

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This article was originally published by Qassim University and was migrated to Scientific Scholar after the change of Publisher.

Abstract

Heterocyclic compounds are compounds containing five triple or quaternary cyclic atoms of N, O, S. They have distinctive features that show their importance in many pharmaceutical formulations used in medicinal chemistry. Therefore, heterocycles are of great importance to chemists working in medicine for the development of the chemical field as well. 1,3,4-thiadiazole has become an important building block in organic synthesis due to its wide range of natural substances. Therefore, scientists have paid attention and studied the biological activity of 1,3,4-thiadiazole. 1,3,4-thiadiazoles and their activity against cancer and also against microbes were evaluated as 1,3,4-thiadiazole sulfonamides were evaluated and it was found that compounds containing the sulfonamide part are effective as virus inhibitors.